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Overview
Affiliations
AffiliationTelephone
Professor in the Department of Chemistry+44 (0) 191 33 42091
Fellow of the Wolfson Research Institute for Health and Wellbeing

Biography

Research Interests
Materials for sensing, delivery of actives and drugs

We use liposomes, gels and nanomaterials for in-vivo and in-vitro sensing and delivery. The aim is to develop materials that are biocompatible and ’soft’ for replacing solid state devices. The picture on the left shows a PEDOT/CNT modified biocompatible hydrogel which is electrochemical and mechano sensitive.

This work additionally extends to collaborative work with Procter and Gamble for delivery of actives.

Electrochemical measurement of electron and ion transport at liquid-liquid interfaces

Electrochemistry at the liquid‑liquid interface or the interface between two immiscible electrolyte solutions (ITIES) is a simple model of the biological membrane. It provides a means to study the transfer of a wide range of compounds. These electrochemical processes are especially interesting as they can provide information about the non-redox-active species, whole cells, bioactive molecules and ions. We have used the liquid liquid interfac for studying chiral interctions between drugs and proteins, lipid‑bioactive molecule interactions amongst others.

Current collaborative work with Procter and Gamble extends to studying detergency at a liquid-liquid interface.

Interactions of lipid membranes and cell mimics with bioactive molecules

Electron and ion transfer properties of supported and black lipid membranes modified with membrane associated molecules are studied using electrochemistry, impedance spectroscopy and Scanning Electrochemical Microscopy.

Developing sensors and biosensors for environmental, clinical and pharmaceutical monitoring.

We have developed sensors electrochemical sensors for a wide range of applications in novel formats includingchiral sensors, multi‑analyte sensing platforms microelectrode arrays, chemically responsive micro grippers, sensors for formaldehyde monitoring amongst others.

Research interests

  • Electrochemistry
  • Sensors
  • Charge Transfer at Interfaces

Esteem Indicators

  • 2000: Esteem indicators from 2007-2014:

    Notable Invited, Keynote, Plenary Lectures:

    • Portuguese Electrochemical Society Annual Meeting, Coviliha, Plenary , 2007
    • Golden Jubilee of Bhabha Atomic Research Centre, Trombay, India, conference on Electroanalysis. Plenary Talk and workshop, 2008
    • International Society for Electrochemistry, Turku, Finland, Keynote,2011
    • Annual Meeting of Indian Society of Electrochemistry Plenary, 2012
    • Bioelectrochemistry workshop, Lochow, Poland,2013
    • International Society for Electrochemistry, Santiago de Queretaro, Mexico,2013
    • International Society of Electrochemisry, Malmo, Sweden,Keynote,2014
    • Electrchem 2014, New Horizons in Electrochemistry , Loughborough UK, Keynote, 2014
    •  ECHEMS 2014 , Electrochemistry in Molecular Understanding, Wells, UK, invited , 17-20 June 2014

    Chairs at International conferences:

    • Chair of the electroanalytical session at the 57th Annual Meeting of the International Society of Electrochemistry, Edinburgh., 2007
    • Organiser and chair of symposium on Electroanalysis at Electrochem 2012, RSC Electrochemistry Group i, 2012
    • Chair of the Analytical Research Forum 2012, Durham.2012
    • Scientific committee member and symposium chair in Faraday Discussion 164, Electroanalyses at the Nanoscale,.2013
    • Chair of Electrochem 2015, Moleculear Materials in Electrchemsitry, 13-15 Sept 2015

Publications

Journal Article